• We modelled how the loss of

  2019-04-20

  

  We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction

• The Sustainable Development Goals can be achieved through

  2019-04-20

  

  The Sustainable Development Goals can be achieved through environmental prevention of diseases without an additional burden on resources. The WHO avoidable early environmental exposures initiative emphasises that the unrecognised health risks are most damaging to the human population. An absence of

• The need for better measurement

  2019-04-20

  

  The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t

• La cam se mantiene hasta nuestros d as en resistencia

  2019-04-20

  

  La cam se mantiene hasta nuestros días en resistencia y se ha caracterizado como una organización radicalizada en el rescate de su cultura en, y desde, sus territorios, insiste en ello como condición para la reconstrucción de sus formas religiosas, lengua, autoridades, etc., ya que la autonomía que

• br INTRODUCCI N Con la incorporaci n de

  2019-04-20

  

  INTRODUCCIÓN Con la incorporación de los derechos colectivos de los pueblos indígenas en la normatividad internacional de los derechos humanos, se inicia una nueva etapa en la conflictiva relación entre las bases fundacionales del poder político moderno y la diversidad cultural, en tanto aquellas

• C sar y Rosa Mar a posan

  2019-04-20

  

  César y Rosa María posan por la insistencia de Menéndez. Montes tiene muy claro ese momento, “yo estaba recargado en mi mano y entonces Mario vio eso y le dice irak pathway Rodrigo, ‘¡Rodrigo ven, ven!’, y el otro viene corriendo, yo volteo y Mario me dice: ‘ponte así como estabas, no te muevas, per

• Data on chloroquine resistance from Pakistan is

  2019-04-20

  

  Data on chloroquine resistance from Pakistan is scarce, even in the most recent global analysis. Nevertheless, in 2013, the emergence of the F1076L mutant of the gene—the purchase glp-2 responsible for chloroquine resistance—in in Pakistan highlights the imminent threat of resistant . In 2015, th

• br Sustained monomorphic ventricular tachycardia br Monomorp

  2019-04-19

  

  Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occur

• Currently RFCA is indicated if pharmacologic therapies are

  2019-04-19

  

  Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter

• Although other risk markers such as high amplitude

  2019-04-19

  

  Although other risk markers such as high amplitude J waves in the inferior leads have been suggested, a better scheme for risk stratification is necessary. The presence of a type I BS ECG pattern indicates the necessity for ICD Phos-tag Acrylamide in patients with syncope of unknown causes. Current

• br Conclusions br Study limitations br Conflict of interest

  2019-04-19

  

  Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum b

• br Methods br Results br Discussion One

  2019-04-19

  

  Methods Results Discussion One of the hallmarks of cancer is the ability of cancer glutathione s-transferase to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory m

• Introduction Pulmonary vein isolation PVI is an established

  2019-04-19

  

  Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a

• Recently a reciprocal fusion between YPEL

  2019-04-18

  

  Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological ma

• HSP plays a crucial role as a main

  2019-04-18

  

  HSP90 plays a crucial role as a main molecular chaperone in the regulation of proteostasis such as protein refolding under stress conditions [30]. It has been established that HSP90 binds a client protein such as Raf-1 and forms more continuous and stable functional complex [29]. On the other hand,

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