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pdgfr inhibitor br Experimental Procedures br Author Contrib
2018-10-24
Experimental Procedures Author Contributions Acknowledgments Introduction Induced pluripotent stem pdgfr inhibitor (iPSCs) have similar properties as embryonic stem cells (ESCs), such as self-renewal and differentiation capacity (Park et al., 2008c; Takahashi and Yamanaka, 2006). Reprog
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The AGM explant culture is known
2018-10-24
The AGM explant culture is known to increase HSC activity. Whether the increase in AGM explant HSCs is due to the expansion and shift in BMP-activation status of existing HSCs, or the new generation of HSCs (non-BMP-activated), or both, remains unclear. Secondary transplantations of GFP+ and GFP− BM
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Specific histone modifications are currently used
2018-10-24
Specific histone modifications are currently used to define Phos-tag Acrylamide regions with different regulatory functions. In particular, monomethylation of lysine 4 of histone 3 (H3K4me1) characterizes enhancer regions, whereas its trimethylation (H3K4me3) defines promoters (Ernst et al., 2011;
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The role of Wnt catenin signaling
2018-10-24
The role of Wnt/β-catenin signaling in reprogramming has also been investigated. Exogenously introduced WNT3A enhances fibroblast reprogramming in the absence of c-Myc (Marson et al., 2008). Knockdown or knockout of T cell factors or treatments with several drugs that control the Wnt pathway can cha
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hydroxychloroquine sulfate br Results br Discussion The inte
2018-10-24
Results Discussion The interest in directed cell-fate determination in stem cell biology and regenerative medicine has been increasing over the years. However, due to the complexity of GRNs, identification of cell-fate determinants and their functionally important subnetworks (GRN motifs) that
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During normal development cytokine availability fluctuates p
2018-10-24
During normal development, cytokine availability fluctuates partly because HSCs have to move from one bax pathway to another, such as from FL to BM (Mazo et al., 2011). HSCs need to overcome apoptosis induced by cytokine fluctuation during normal development (Kohli and Passegue, 2014). Factors contr
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As a marker of cochlear supporting
2018-10-24
As a marker of cochlear supporting cells, we assessed P27Kip1 localization in iCx26GJCs. P27Kip1 is a cyclin-dependent kinase inhibitor that is thought to play a role in maintaining the postmitotic state of cochlear supporting angiopoietin such as the Deiters\' cells and outer- and inner-sulcus cel
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Introduction Open chromatin is a global constitutive feature
2018-10-24
Introduction Open chromatin is a global, constitutive feature of naive embryonic stem K03861 (ESCs), which are characterized by low levels of repressive histones and DNA methylation (Gaspar-Maia et al., 2011; Meshorer and Misteli, 2006). Diverse factors are required to maintain ESC chromatin in a d
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Let us assume that the traps are
2018-10-24
Let us assume that the traps are distributed non-uniformly over the layer bulk, specifically, The mek162 equation Here is the diffusion coefficient; wis the mass hydrogen concentration in the layer; the source terms describe hydrogen flow from the traps inside the layer. Let us use the express
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Indeed recent qualitative studies support
2018-10-24
Indeed, recent qualitative studies support the idea that discrimination exists against the poor in Canada for their poor oral health (Bedos, Levine & Brodeur, 2009; Ravitch & Riggan, 2012; Shankardass, Lofters, Kirst & Quiñonez, 2012; Vallittu, Vallittu & Lassila, 1996). Our study attempts to assess
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The EITC one of the
2018-10-24
The EITC, one of the federal government’s largest anti-poverty programs, has been a recent exception. Research has begun to link improved income resulting from EITC benefits to improved health outcomes (Baughman & Duchovny, 2016; Muennig, Mohit, Wu, Jia & Rosen, 2016; Hoynes, Miller and Simon, 2015;
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Columns in Table present the estimated
2018-10-23
Columns 1–6 in Table 4 present the estimated results for the dependent variable average Prova Brasil test scores in Portuguese for 5th grade students in basic education. Each column presents the results of an estimator (LS, FE and RE) with the matching and additional covariates. All the ATT measurem
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As seen in Table the majority
2018-10-23
As seen in Table 1, the majority of firms in our sample are not listed on the stock market as well as they are SME. Firms in our sample have around 416 employees where their exports represent only 6% of their revenues. Overall, figures represent what is expected: Firms listed on the stock market are
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Type interferon signaling has been identified not only as
2018-10-23
Type 1 interferon signaling has been identified not only as a biomarker of TB disease but also as a key player in mycobacterial disease pathogenesis. In leprosy, IFNγ-induced antimicrobial genes were mostly detected in self-healing tuberculoid lesions, whereas type I interferon related genes were pr
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Strengths of this analysis include that the
2018-10-23
Strengths of this analysis include that the biomarker assay was analytically validated, the data were from a randomized clinical trial, and the hypothesis was prospectively stated prior to data unblinding (Khleif et al., 2010). The fact that a single biomarker was identified minimized the potential
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