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In countries such as China where there
2021-08-18
In countries such as China where there is a high commercial production of rice, the use of rice husk ash (RHA) as an alternative cementing material can become a great asset for environmental rehabilitation and address the difficult disposal issues associated with this agricultural waste [23]. RHA po
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In the present study it was particularly of interest that
2021-08-18
In the present study, it was particularly of interest that intravesical administration of PGE2 evoked ONO-8130-reversible rapid phosphorylation of ERK in the L6 spinal cord. Detection of phosphorylated ERK is now often used as a marker for somatic and visceral nociception, including JTP-74057 pain
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We found that Th cells
2021-08-18
We found that Th17 cells, derived either from in vivo immunization or in vitro polarization under pathogenic conditions (in presence of IL-23 and/or IL-1β) expressed high levels of EBI2. In contrast, Th17 vomitoxin that were generated in absence of IL-23 or IL-1β lost EBI2 expression during differe
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In this study Oncomine GEO and TCGA
2021-08-18
In this study, Oncomine, GEO and TCGA databases were used to analyze the expression of UBE2S gene in HCC and normal liver tissues to determine the relationship between UBE2S expression and prognosis of hepatocellular carcinoma. The potential function of UBE2S in HCC was analyzed by screening UBE2S c
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br Materials and methods br Results br Discussion Ubiquitina
2021-08-18
Materials and methods Results Discussion Ubiquitination is an important eukaryotic process that defines the fate of proteins and their functionality. It has multiple roles in cell survival, differentiation and development (Glickman and Ciechanover, 2002). Ubiquitination is usually known as
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However a two receptor model presents a mystery of how
2021-08-18
However, a two-receptor model presents a mystery of how MBns know whether they are receiving an acquisition or forgetting signal from the PPL1 DAns. The most attractive explanation for this is that the two receptors might have different signaling properties and mobilize distinct signaling cascades.
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A similar pattern was observed for both tissues
2021-08-18
A similar pattern was observed for both tissues of P. harpagos, evidencing the absolute predominance of acetylcholinesterase. As observed, no effects were attributed to Iso-OMPA. The hypothesis that the major cholinesterasic form is AChE was reinforced considering the higher hydrolytic activity, whi
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Despite the significant associations between TNF
2021-08-17
Despite the significant associations between TNF-α and TRAIL in our results, the use of a single top cytokine in predicting sPTB is limited, and the previous study using the specific candidate cytokines failed to accurately predict the risk for sPTB in asymptomatic women, with AUC ranged from 0.48 t
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Introduction Cytochrome P CYP A is the most important enzyme
2021-08-17
Introduction Cytochrome P450 (CYP)3A is the most important enzyme involved in the metabolism of 30–40% of currently prescribed drugs [1]. The L-Adrenaline level and activity of CYP3A show large intra- and inter-individual variability, which contributes to unpredictable drug response and toxicity.
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Acidic substituents showed moderate biochemical activity but
2021-08-17
Acidic substituents () showed moderate biochemical activity, but these compounds showed reduced cellular potency. Additional compounds bearing a carboxylic Bupivacaine HCl were also prepared and tested (data not shown). All of acidic compounds showed low cellular potency regardless of their biochem
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Pattern separation is a process that takes place in the
2021-08-17
Pattern separation is a process that takes place in the hippocampus and more specifically in the dentate gyrus (DG) and Cornu Ammonis region 3 (CA3) (Morris, Churchwell, Kesner, & Gilbert, 2012). The main source of input in the hippocampus is derived from the enthorinal cortex (EC) that mainly proje
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Neuropsychological studies of adults with problem gambling i
2021-08-17
Neuropsychological studies of adults with problem gambling indicate impairments in many cognitive areas including inhibition, working memory, decision-making, cognitive flexibility, and executive planning (Ledgerwood et al., 2012, Goudriaan et al., 2006). Dopamine is a neurotransmitter that regulate
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The second part of this study evaluated the role of
2021-08-17
The second part of this study evaluated the role of CK1 in the eFABP4 cellular uptake in endothelial cells. By blocking CK1 expression using a specific siRNA, we corroborated that the presence of CK1 was fundamental for FABP4 cellular uptake and internalization in endothelial cells, thus decreased m
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It is common for plants that
2021-08-17
It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot pkc inhibitors ratio compared with plants in the INORG-P treatment. Additionally, greater allocation of C t
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Although it remains an unsettled issue evidence favors that
2021-08-17
Although it remains an unsettled issue, evidence favors that the endothelin ETA nitric oxide synthase inhibitor may play a more important pathological role. While both endothelin ETA and ETB receptors are found in most tissues, endothelin ETA receptor is the predominant receptor responsible for the
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