• br Experimental section br Results br

  2020-06-09

  

  Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised UCF 101 mg did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a patient by

• br Conflict of interest br Acknowledgments Part of

  2020-06-09

  

  Conflict of interest Acknowledgments Part of this work was supported by Institut Francais en Egypte, and the Academy of Scientific Research and Technology in Egypt under the frame of “Imhotep Project N°: 31681XL” and “STDF/IFE project N° 30630″ Introduction NSAIDs play an important role in

• br Acknowledgements This work was financially supported by I

  2020-06-09

  

  Acknowledgements This work was financially supported by Industrial Technology Institute, Sri Lanka through funds received from Sri Lankan Government Treasury (TG13/69). G. D. Liyanaarachchi received postgraduate research scholarship grant from National Science Foundation Sri Lanka (NSF/SCH/2017/0

• Therefore HNE is an attractive

  2020-06-09

  

  Therefore, HNE is an attractive therapeutic target and the design of new HNE inhibitors is a demanding field that has been extensively investigated in order to provide inhibitors with new molecular architectures, including the potent oxo-β-lactam class [14]. In the present work, a coumarin-based oxo

• Most xenobiotics undergo biotransformation before being

  2020-06-09

  

  Most xenobiotics undergo biotransformation before being excreted. Such biotransformation is classified into two phases. In the first phase, the lipophilic substrate is oxidized by the cytochrome P-450 (CYP450) enzyme system, which introduces a single oxygen 2×Taq PCR Master Mix(with dye) into the mo

• Many researchers studied the experimental investigation

  2020-06-09

  

  Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad

• br Acknowledgments We are thankful to the University of Guil

  2020-06-09

  

  Acknowledgments We are thankful to the University of Guilan Research Council for partial support of this work. Introduction It is significant to predict the mass, number and velocity distribution of BAD generated by RHA subjected to penetration of EFP by the thickness of target and the impact

• br Molecular genetics Based on the genetic mutations

  2020-06-09

  

  Molecular genetics Based on the genetic mutations associated with their development, sarcomas are subdivided into two distinct classes. One class is composed of tumors bearing complex karyotypic abnormalities with no particular pattern. The second class, which includes Ewing sarcoma, encompasses

• Information on the mechanism by

  2020-06-08

  

  Information on the mechanism by which parasite infections promote ECM degradation is limited (McKerrow et al., 1983; Andrade, 1994; Lu and Lai, 2013; Thibeaux et al., 2014). The interaction of plasminogen-plasmin with proteins of microorganisms, including bacteria, has been suggested to play a key r

• Lymphocyte mobility and homing is modulated

  2020-06-08

  

  Lymphocyte mobility and homing is modulated by the chemoattractant receptor subfamily of G protein-coupled receptors (GPCRs) (Campbell et al., 2003, Rot and von Andrian, 2004). B cell migration and position are controlled to a large extent by the lymphoid chemokines CXCL13, CXCL12, CCL19, and CCL21

• Main Text Post translational modifications by ubiquitin Ub a

  2020-06-08

  

  Main Text Post-translational modifications by ubiquitin (Ub) and ubiquitin-like proteins (Ubl) regulate a diverse array of cellular and physiological processes including protein degradation, localization, and activation. While ubiquitination has primary responsibility for targeting substrates for p

• br Experimental procedures br Introduction Protein kinases r

  2020-06-08

  

  Experimental procedures Introduction Protein kinases represent one of the largest enzyme cholesterol absorption inhibitor in the human genome and act as signaling mediators in a variety of cellular processes (Manning et al., 2002). Because many diseases are associated with aberrant protein ki

• Ligand independent constitutively active variants

  2020-06-08

  

  Ligand-independent, constitutively active variants have also been found in receptors with associated tyrosine kinases. In approximately 60% of patients harboring inflammatory hepatocellular adenomas (IHCAs), these adenomas have been caused by small in-frame deletions in the cytokine-binding domain o

• In humans CYP A major isoforms of CYP As in

  2020-06-08

  

  In humans, CYP3A4/5, major isoforms of CYP3As in the liver, have variants that reduce the enzyme activities [33], [34]. In addition, Werk et al. recently reported the first case of a complete failure of CYP3A enzyme activity due to homozygous loss-of-function mutation of CYP3A4 combined with nonfunc

• To ascertain that the slower

  2020-06-08

  

  To ascertain that the slower migrating bands represented phosphorylated CDK5, we performed a phosphatase assay. Lysates of Mitomycin C co-expressing p35 and either WT or D144N CDK5 were immunoprecipitated using an anti-p35 antibody. The immunoprecipitates were then dephosphorylated using SAP along

15649 records 805/1044 page Previous Next First page 上5页 801802803804805 下5页 Last page